There is a great deal of activity in the management of the Open University at the moment and there is a very complex array of "workstreams" working on "transforming" and "redesigning" the way the university works and as a tutor, I hear about them through messages and meetings such as the AL Assembly last weekend. However, the issue of Brexit and its effects on the university does not seem to be mentioned often enough.
I would think Brexit will have a very significant effect on the Open University (and probably all other British universities as well). A first effect will be on the many EU staff in the university and their morale and retention in a hostile environment. A second will be on the recruitment of students. A colleague commented on how she has fewer students than before from Eastern and Central Europe. The atmosphere around Brexit and hostility towards EU citizens might have led to a less positive attitude towards the UK in general and UK universities in particular. A third effect is the reduction in EU research funding.