Interpreting and adapting Cochrane’s “PICO”framework to the example of a systematic review of literature on type-2 diabetes concerning patients who may be positively affected as a result of the possible interventions offered by a new patented drug such as Ozempic, what one finds is a perfect example of a T1 or T2 research opportunity. Depending on how you might categorise such a study.
But because it is scientific in its premise first and foremost as opposed to being focused on the science of applicability we’ll call it T1.5. One might define the T1.5 research question (using a PICO systematic review) as follows:
- Population: Working age adults with type-2 diabetes
- Intervention: Measuring the long-term effects of Ozempic (Semaglutide)
- Comparisons: Studies that measure against no treatment
- Outcomes: Blood sugar levels (for example)
Therefore, the appropriate title of the study in the above example may be:
“Measuring the long-term effects of Ozempic (Semaglutide) on blood sugar levels in working age adults with type-2 diabetes.”
What I love about this it is a very simple and repeatable formula for successful research question design. More from me shortly.